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Volume 6, Issue 2 (8-2020)                   IJCA 2020, 6(2): 0-0 | Back to browse issues page

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Bahrami A, Ahmadi M, Yousefi Z, Rezaei N. Evaluation of risk factors and phenotypes of patients with asthma. IJCA 2020; 6 (2)
URL: http://ijca.iums.ac.ir/article-1-188-en.html
Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Dr. Qarib St, Keshavarz Blvd, Tehran14194, Iran.
Abstract:   (971 Views)
Backgrounds: Asthma is a common disease in the whole world that imposes social, economic and therapeutic burden on the individual and society, a heterogeneous disease that has multiple genetic and environmental factors affecting its occurrence and severity. There are several risk factors for asthma that include atopy, sex, smoking, respiratory infections, and obesity. Since asthma is a chronic disease, during the life of the patient it involves many issues that sometimes reduce the quality of life, so we decided to explore and better understand these risk factors in the pediatric age group, by knowing The more these risk factors can reduce the risk of an outbreak or exacerbation of asthma from childhood.
Methods: In this study, children from age of 3 to 12 years with a definite diagnosis of asthma who referred to Ali Asghar Hospital from December 2017 to November 2018, were referred to the Allergy Clinic. In this period, 475 children were eligible for examination. Therefore, based on the data of the case, with the help of questionnaires, information was collected about asthma phenotypes and their risk factors.
Asthma diagnosis has been proven in all of these children and this child should not have any other underlying conditions and should not take any special medication other than those prescribed for asthma. This information is entered directly by the physician into the algorithm, and then the data are the subject of the response to the treatment because of the prevalence, prognosis, and scope. The results were analyzed using SPSS software. In this study, 8 phenotypes were included: atopic asthma, non-atopic asthma, asthma associated with vising, asthma with symptoms of attack, asthma-related infections, and asthma-dependent asthma and aspirin-dependent asthma. In this research, the frequency of these phenotypes in asthmatic patients in the studied population is calculated.
Results: In this study, the role of risk factors related to asthma was studied. Among these, the symptoms of allergic rhinitis, family history of smoking, age of birth, exacerbation of symptoms during colds and exercise, gender and number of admissions were the most frequent Gave.
Conclusion: The risk factors have a direct and significant relationship with asthma symptoms.
     
Type of Study: Original Research | Subject: Allergy & Immunology

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