Showing 5 results for Torabi
Hasan Otukesh, Ala Torabi, Rozita Hoseini, Parnian Kheirkhah Rahimabad, Mitra Mehrazma,
Volume 2, Issue 4 (10-2016)
Abstract
Background: Nephrotic syndrome and type 1 diabetes mellitus are two common chronic conditions in children.
Co-existence of these conditions is an extremely rare finding.
Case presentation: This report presents a 6-year-old boy who was diagnosed with nephrotic syndrome five
years ago and type 1 diabetes mellitus in infancy. Renal biopsy showed membranous glomerulonephritis, which
is a rare histopathology underlying nephrotic syndrome in children.
Conclusion: Co-existence of nephrotic syndrome and type 1 diabetes mellitus may suggest a mutual immunological
basis for both conditions.
Dr Ahmad Bahrami, Dr Shirin Sayyahfar, Dr Gholareza Bahoush, Dr Mojtaba Shetaban, Dr Mryam Vafapour, Sara Torabi,
Volume 3, Issue 4 (11-2017)
Abstract
Leukocyte adhesion deficiency (LAD) is a rare inherited primary immunodeficiency disorder characterized by the presence of a defect of phagocytic function resulting from a lack of leukocyte cell surface expression of β₂ integrin molecules (CD11 and CD18) that are essential for leukocyte adhesion to endothelial cells and chemotaxis. It is characterized by delayed separation of the umbilical cord, recurrent bacterial and fungal infections, defective wound healing, blood neutrophilia and a high mortality rate at an early age. Here, we report a case of LAD in a 38 days old male with recurrent hospitalizations because of severe pneumonia and positive bacterial cultures is presented. His medical history included neonatal sepsis and delayed umbilical cord detachment. Laboratory studies showed marked leukocytosis with predominance of neutrophils and decreased CD11b and CD18.
Ahmad Bahrami, Behzad Haghighi Aski, Ali Manifi Anari, Zeinab Zohrevandi, Sara Torabi,
Volume 5, Issue 1 (8-2019)
Abstract
A 7.5-year-old male with mild intermittent asthma presented with a complaint of sudden shortness of breath and subsequently cyanosis that led to respiratory arrest.
Although Asthma is the most prevalent chronic respiratory disease globally, it is affecting children through all ages (1). This condition is described as a chronic inflammatory airway disease. However, there are several phenotypes of this chronic inflammatory that are seen among the pediatric population (2).
According to guidelines, asthma has four levels of mild intermittent, mild persistent , moderate persistent , severe persistent that the classification of which are based on the severity of symptoms, spirometry parameters including forced expiratory volume in one second (FEV1) and peak expiratory flow(PEF)(3).
At each level the patients can experience the acute asthma exacerbation which is defined as the respiratory distress that does not respond to outpatients’ treatments either with or without history of corticosteroid therapy. Each episode of this condition can cause the respiratory failure. Therefore, acute asthma is defined as a medical emergency in pediatric population which is leading to nearly half of millions of pediatric intensive care unit (PICU) hospitalizations annually (4-6)
In this study, we reported a case of mild intermittent asthma with rapid decompensation to respiratory arrest.
Shirin Sayyahfar, Sara Torabi, Faranak Davoodzadeh,
Volume 6, Issue 1 (5-2020)
Abstract
Introduction: Considering that prevoius investigation has included more adult age range, this study aimed to evaluate the agreement between TST and Quantiferon in kidney disease children who are candidate for immunosuppressive medications.
Methods: In this cross sectional study, 31 children with renal disease including nephrotic syndrome and renal transplant candidates nominated for immunosuppressive drugs were evaluated from the point of LTBI. These children underwere TST and QFT. Physical examination and chest x-ray was conducted in all patients who were positive for QFT or TST to rule out active TB. Finally, the data were entered into statistical software SPSS v. 16 and were analyzed.
Results: In this study, 31 children including 17 (54.8%) new case of nephrotic syndrome and 14 (45.2%) kidney transplant candidates with a mean age of 6.86 (SD= 4) years were evaluated from whom 10 (32.3%) were female and 21 (67.7%) were male. The average duration of nephrotic syndrome was 1.3(SD= 12.12) weeks. The average duration of ESRD in children undergoing kidney transplantation was 6.35 (SD= 2.83) years and the average duration of dialysis was 1.72 (SD= 1.25) years. QFT test was negative in all patients in both groups and PPD test was positive in 1 (5.9%) patients with nephrotic syndrome; the difference was not statistically significant (p Value = 0.35).
Conclusion: QFT test has a high negative predictive value as well as a high diagnostic accuracy compared with TST and thus QFT and TST have a similar diagnostic performance to assess TB, however due to lower cost-benefit of TST, this test is more preferred to QFT.
Ahmad Bahrami , Sara Torabi, Javad Azadi,
Volume 6, Issue 1 (5-2020)
Abstract
Background: Asthma is one of the most common chronic diseases all over the world, which impacts socioeconomics of families and health care systems. We aimed to investigate the economic burden of pediatric asthmain Iran and to examine its variability depending on asthma severity.
Methods: In a descriptive-analytical study 141 pediatric asthmatic patients, who referred to pediatric referral centers in Tehran , included from September 2018 to September 2019 . in an interview with parents we evaluated direct medical costs of asthma including physician fees, admission fees, medication costs and direct nonmedical costs including transportation,hoteling and others. Data were statistically analyzed for finding association between the costs and disease severity (3 groups of mild, moderate and severe were defined)
Result: 75 patients (65.8%) were male and 39 patients (34.2%) were female with the age range of 1-16 yr old were included. We found the mean annual cost per child was approximately 205 dollars . In this study, 83% of costs were related to direct medical costs, 69% of which were hospitalization costs Direct non-medical costs were estimate 17% including 51 %transportation costs and 49% hoteling costs. Also, 37% of the patients had severe disease severity, with the majority of the costs being allocated to the patients in this group
Conclusion: Since there is a close correlation between the costs and the severity of the disease, there is also a significant increase in costs If the disease is not controlled, it can be concluded that early diagnosis and control of the disease can have a significant role in reducing costs.
