en گزارش مورد case report Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis.<br> Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric residue and bloody stool, severe eosinophilia and pneumatosis intestinalis in abdominal X-ray that treated as necrotizing enterolitis and fully recovered without the management of allergic enterocolitis.<br> Conclusions: &nbsp;severe eosinophilia may be encountered during the episodes of NEC and it may propose the diagnosis of allergic enterocolitis but further studies is needed to clarify this association.&nbsp; Necrotizing enterocolitis, Eosinophilia, Prematurity 0 0 http://ijca.iums.ac.ir/browse.php?a_code=A-10-59-1&slc_lang=en&sid=1 Golnaz Gharehbaghi golnaz.gharehbaghi@gmail.com 1003194753284600553 1003194753284600553 Yes Aliasghar Children's Hospital, Iran University of Medical Sciences Arash Bordbar drarashbordbar@gmail.com 1003194753284600554 1003194753284600554 No Akbar abadi Hospital, Iran University of Medical Sciences Setareh Mamishi smamishi@sina.tums.ac.ir 1003194753284600555 1003194753284600555 No Pediatric Infectious Diseases Research Center, Tehran University of Medical Sciences