en گزارش یک مورد آریتمی قلبی و نقص در چسبندگی لکوسیت ها گزارش مورد case report Leukocyte adhesion deficiency (LAD) is a rare inherited primary immunodeficiency disorder characterized by the presence of a defect of phagocytic function resulting from a lack of leukocyte cell surface expression of &beta;₂ integrin molecules (CD11 and CD18) that are essential for leukocyte adhesion to endothelial cells and chemotaxis. It is characterized by delayed separation of the umbilical cord, recurrent bacterial and fungal infections, defective wound healing, blood neutrophilia and a high mortality rate at an early age. Here, we report a case of LAD in a 38 days old male with recurrent hospitalizations because of severe pneumonia and positive bacterial cultures is presented. His medical history included neonatal sepsis and delayed umbilical cord detachment. Laboratory studies showed marked leukocytosis with predominance of neutrophils and decreased CD11b and CD18.<br> &nbsp; Immunologic deficiency, Leukocyte-adhesion deficiency syndrome, CD11/CD18. 0 0 http://ijca.iums.ac.ir/browse.php?a_code=A-10-65-1&slc_lang=en&sid=1 Ahmad Bahrami احمد بهرامی bahrami.ai@iums.ac.ir 10031947532846001094 10031947532846001094 No Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Shirin Sayyahfar شیرین سیاح فر sayyahfar.sh@iums.ac.ir 10031947532846001095 10031947532846001095 No Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Gholareza Bahoush غلامرضا باهوش grbahoush1968@gmail.com 10031947532846001096 10031947532846001096 No Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Mojtaba Shetaban مجتبی شتابان bahrami_a@yahoo.com 10031947532846001097 10031947532846001097 No Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Mryam Vafapour مریم وفاپور vafapourm@gmail.com 10031947532846001098 10031947532846001098 Yes Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Sara Torabi 10031947532846001099 10031947532846001099 No Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.