en آنافیلاکسی به ایمونوگلوبین وریدی در یک بیمار CVID گزارش مورد case report Common variable immune deficiency disease (CVID) is one of the most common primary immunodeficiency disorders. It causes reduction of immunoglobulin levels and specific antibodies production and enhancement of recurrent and chronic infections risk, especially respiratory infections and gastrointestinal tracts. Here, we report a case of CVID in a 3 years old male with recurrent hospitalizations because of gastroenteritis and sinobronchitis infections that was treated as allergic disease for a long time but he does not improved. During receiving IVIG he had sever reaction and treated as anaphylaxis an admitted to ICU.&nbsp;<br> &nbsp; primary immunodeficiency disorders, CVID, immunoglobulin, IVIG 0 0 http://ijca.iums.ac.ir/browse.php?a_code=A-10-65-2&slc_lang=en&sid=1 Ahmad Bahrami احمد بهرامی bahrami.ai@iums.ac.ir 1003194753284600715 1003194753284600715 No Iran university of mdeical sciences دانشگاه علوم پزشکی ایران Maryam Vafapour مریم وفاپور vafapourm@gmail.com 1003194753284600716 1003194753284600716 Yes Iran university of mdeical sciences دانشگاه علوم پزشکی ایران