fa دیگر Other پژوهشي اصیل Original Research <p>Background and Objective: To assess the incidence and risk factors of upper gastrointestinal bleeding in children admitted to pediatric intensive care unit for more than 6 hrs.<br> Methods: We prospectively collected medical records of children between 1 month and 18 years old admit-ted to our 10 bed PICU of a tertiary care university hospital between December 1, 2014 and May 30, 2015. De-mographic data, admission diagnosis and basic laboratory data were recorded. We defined upper gastrointestinal bleeding (UGI) as any evidence of blood in nasogastric aspirates, hematemesis and melena witnessed between minimum 6 hours to maximum 5 days after admission. We documented it and detected previously described factors for UGI bleeding such as mechanical ventilation, coagulopathy, organ failure, feeding, and drug prophy-laxis. Finally data were used in a multivariate analysis.<br> Results: Of 157 medical records, 148 patients were eligible. The incidence of UGI bleeding was 34.45%. The most common indication for PICU admission was respiratory system dysfunction (32.2%). Mechanical ven-tilation, thrombocytopenia and prolonged PT and PTT were the significant factors in our study using univariate analysis and mechanical ventilation was the only significant risk factor using multivariate analysis<br> Conclusion: The incidence of UGI bleeding in PICU admitted patients is significant and mechanical ventila-tion is the most important risk factor for GI bleeding.</p> Incidence, Risk factor, Upper gastrointestinal bleeding 11 16 http://ijca.iums.ac.ir/browse.php?a_code=A-10-1-33&slc_lang=fa&sid=1 Saeedeh Haghbin Haghbins@sums.ac.ir 1003194753284600219 1003194753284600219 No Shiraz University of Medical sciences, Shiraz , Iran Ali Manafi Anari amanafi55@yahoo.com 1003194753284600220 1003194753284600220 Yes Iran University of Medical sciences, Tehran , Iran Zahra Serati zserati@yahoo.co.uk 1003194753284600221 1003194753284600221 No Shiraz University of Medi-cal sciences, Shiraz , Iran Khashayar Aflaki aflakik@yahoo.com 1003194753284600222 1003194753284600222 No Shiraz University of Medi-cal sciences, Shiraz , Iran Behzad |Haghighi Aski haghighi_behzad@yahoo.com 1003194753284600223 1003194753284600223 No Iran University of Medical sciences, Tehran , Iran Mohamad Reza Navaei far dr.navaifar@gmail.com 1003194753284600224 1003194753284600224 No Mazandaran University of Medical sciences, Sari , Iran