Research Center for Immunodeficiencies, Children’s Medical Center Hospital
Abstract: (1118 Views)
Severe combined immunodeficiency is a rare, fatal syndrome of diverse genetic cause in which there is combined absence of T-lymphocyte and B-lymphocyte function (and in many cases also natural killer, or NK lymphocyte function). These defects lead to extreme susceptibility to serious infections. Without intervention, the T and B-cell dysfunction usually results in severe infection and death in children by age 2 years. Here, we report a case of SCID in a 37-day-old male infant was admitted to pediatric intensive care unit (PICU) in our hospital with complain of the right knee swelling.
Keywords: primary immunodeficiency disorders, SCID, septic arthritis