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Volume 2, Issue 4 (10-2016)                   IJCA 2016, 2(4): 5-9 | Back to browse issues page

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Sobouti B, Noorbakhsh S, Ashraf H, Ashraf -Talesh S. Use of Probiotic for the Treatment of Acute Rotavirus Diarrhea in Children: a Randomized Single-Blind Controlled Trial. IJCA 2016; 2 (4) :5-9
URL: http://ijca.iums.ac.ir/article-1-70-en.html
Resident of pediatrics
Abstract:   (2658 Views)

Background and Objective: Despite consistent evidence that probiotics reduce the duration of diarrhea, there is only weak evidence for their efficacy in reducing the duration of hospitalization. Another source of heteroge-neity for probiotic trials is the type of probiotic being assessed; also, information about combined products is scarce.
Methods: This is a randomized, single-blind controlled clinical trial performed in children hospitalized with acute rotavirus diarrhea carried out at a university hospital in Tehran, Iran. Children were randomly assigned to receive rehydration therapy or the same plus a multi-strain probiotic preparation. The primary outcome was the duration of hospitalization..
Findings: A total of 60 patients with acute diarrhea secondary to rotavirus infection were included; baseline characteristics were similar in both groups. A statistically significant difference in the duration of hospitalization was observed (p <0.001) in children receiving probiotic (5.07 ± 1.30) in comparison to the control group (8.22 ± 2.14).
Conclusion: Results of this study support the use of multi-strain preparation probiotics in treating rotavirus acute diarrhea.

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Type of Study: Original Research |

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